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Used to fill in and smooth wrinkles and folds on the face.
Hylaform® is a widely-used filler of this type.
This is general Information on this popular facial rejuvenation treatment.
We are NOT associated with the makers of Hylaform®.

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Hylaform® is an Avian Dermal Filler<

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General Information: Avian Dermal Fillers ~ Dermal Filler Derived from Birds

The following is general information on avian dermal filler.
It is not medical advice nor authored by a medical professional.
The information was taken largely from the website and may be outdated.
Please visit for the latest information.

Hylaform® - Avian Dermal Filler

Hylaform gel is derived from avian proteins and is injected into wrinkles and facial folds to add volume to facial tissue.
The effect lasts about 12 weeks.
Hylaform® is described on the U.S. Trademark application as: "a prepacked injectable biochemical,namely, hylan gel, for use in tissue augmentation."
U.S. Registered Trademark #2052997

What is Hylaform® gel?

Hylaform gel is sterile and colorless skin (dermal) filler made of chemically modified hylauronic acid derived from a bird (avian) source. Hylauronic acid is a naturally occurring substance found in cell and tissue fluids. It is chemically, physically, and biologically similar in the tissues of all species. Hylaform gel is made from purified, natural hylauronic acid that is gradually absorbed by the body.

How does Hylaform work?

Hylaform works by temporarily adding volume to facial tissue and restoring a smoother appearance to the face. The effect lasts for about 12 weeks. After the initial treatment, "touch-up" treatments may be needed to achieve optimal skin smoothing. Repeat treatments may be needed to maintain the smoothing effect.

When is Hylaform used?

Hylaform is injected by a doctor into areas of facial tissue where moderate to severe facial wrinkles and folds occur. The gel temporarily adds volume to the skin and can give the appearance of a smoother face.

What will Hylaform® accomplish?

Hylaform will help smooth moderate to severe facial wrinkles and folds for about 12 weeks. Some patients in a clinical study needed more than one injection to achieve a satisfactory result.

What are the possible side-effects of Hylaform?

Side effects of Hylaform include:

  • bruising
  • redness
  • swelling
  • pain
  • tenderness
  • raised bumps of skin (nodules).

When should Hylaform® not be used?

Hylaform should not be:

  • used in patients who have a history of known hypersensitivity to avian proteins
  • used for breast augmentation
  • used for implantation into bone, tendon, ligament, or muscle
  • injected into blood vessels because Hylaform may clog the vessels, restricting blood flow and killing tissue (embolization or infarction).

The information found here may not be the latest FDA information on Hylaform.
Please check for the latest FDA information on Hylaform on the FDA website by visiting the main site and typing "Hylaform" in the search box.
FDA Updates

FDA APPROVAL of Hylaform (tm)

New Device Approval
Hylaform - P030032
Product Name: Hylaform
Applicant: Genzyme Corporation
Address: 500 Kendall St., Cambridge, MA 02142
Approval Date: April 22, 2004

For more information about the adverse effects and safety of avian dermal fillers:
Type in "avian dermal fillers".

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